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Vitiligo: Causes, Treatment, and Empowerment

Let's take a moment to think about Michael Jackson, the iconic King of Pop, who mesmerized the world with his music and performances. Many of us can't help but sway to the beat of "Heal the World” and many more. But did you know, that behind the stage lights and fame, he battled a silent but visible foe: VITILIGO? Vitiligo is a skin condition that makes patches of skin lose their colour, creating white spots that stand out against the rest of the skin. It's a common condition, but not everyone knows much about it. This skin condition affects millions worldwide. Many of the world's famous celebrities, from Winnie Harlow to Jon Hamm, have been open about their experiences with vitiligo, bringing awareness to a condition that goes far beyond skin deep. Let's explore vitiligo together—what it is, how it happens, if it runs in families, and what treatments are available, etc.

Michael Jackson battled a silent but visible foe: VITILIGO

What is Vitiligo?

This is a persistent skin condition characterized by the emergence of patches or spots with diminished skin pigmentation, which can occur on any part of the body. The extent and pace of pigmentation loss differ from person to person.

Is all vitiligo of the same type?

There are various types of vitiligo, including:

  • Localized: Characterized by the development of a few spots or patches in specific areas of the body.
  • Generalized: Results in scattered patches of color loss across different parts of the body.
  • Universal: Occurs when individuals experience extensive color loss, affecting most of their skin.
  • Non-Segmental: Involves patches appearing bilaterally on areas such as both knees or both hands.
  • Segmental: Affects one side or part of the body, typically stabilizing after 6 to 12 months with limited spread of color loss.
  • Mixed-Type: A rare variant where individuals exhibit both segmental and generalized color loss beyond the segmental areas.
  • Mucosal: mucous membranes of your mouth and/or genitals are affected.
  • Trichome: causes a pattern resembling a bullseye, with a center that is white or colourless, surrounded by an area of lighter pigmentation, and then an area of your natural skin tone.

Who develops vitiligo? Is it Hereditary?

Vitiligo can affect anyone, regardless of age. However, it often begins before the age of 20 and can even start in childhood for many individuals.

Vitiligo is not directly inherited like some genetic condition

While it is not directly inherited like some genetic conditions, there is evidence to suggest a genetic predisposition. 30% of vitiligo cases are reported to be genetic. It appears to be more prevalent in those with a family background of the condition or those with specific autoimmune disorders such as:

How Does it Occur?

  • Autoimmune condition: Vitiligo starts when the immune system mistakenly attacks and destroys melanocytes, the cells that produce skin colour. This attack reduces melanin production, causing the skin to lose its colour and become white or depigmented.
  • Genetic changes: Researchers are also exploring how family history and more than 30 genes can contribute to this condition. Certain genetic mutations can impact the function of melanocytes.
  • Stress: Emotional or physical stress, such as frequent stress or injury, can alter the production of pigment by melanocyte cells.
  • Environmental triggers: Sometimes, certain events like sunburn, stress, or exposure to chemicals can trigger vitiligo or worsen its effects.

Which body parts can be affected?

Vitiligo usually starts on the hands, forearms, feet, and face. However, it can appear on any part of the body, including mucous membranes (like the moist linings of your mouth, nose, genital and rectal areas), as well as your eyes and inner ears.

Is it Curable? What are the treatments for Vitiligo?

Currently, there is no known cure for vitiligo.

Vitiligo is primarily a cosmetic concern and typically does not pose any harm to your overall health. As a result, treatment is not always necessary. However, in cases where it is extensive or has a significant impact on your emotional health, consulting with your healthcare provider can guide you towards treatment options aimed at achieving a more uniform skin tone by either restoring lost colour or removing remaining colour. Some common treatments include:

  • Medications: No drug can stop the process of vitiligo, corticosteroids or a calcineurin inhibitor sometimes may be able to return color to the white patches of skin.
  • Light therapy or Phototherapy: aims to restore colour to the skin affected by vitiligo with narrow band ultraviolet B .
  • Depigmentation therapy: Depigmentation therapy is a method that aims to match the colour of your unaffected skin with areas affected by depigmentaion using the drug monobenzone.
  • Surgery: Skin grafts involve transferring skin from one part of your body to cover another area. However, risk factors including scarring, infection, or a lack of repigmentation are there.

Can the skin regain its natural colour if you have vitiligo?

Between 10% and 20% of individuals with vitiligo can achieve complete repigmentation if the condition is diagnosed before the age of 20, primarily affects the facial area, or experiences rapid spreading within six months.

Is it contagious?

No, vitiligo is not contagious and cannot be passed from person to person through physical contact.

Living with Vitiligo:

Living with vitiligo can present challenges beyond the physical changes to the skin. Many individuals with this problem experience psychological and emotional effects, including low self-esteem, anxiety, and depression. The visibility of the condition can also lead to social stigma and discrimination, highlighting the need for greater awareness and acceptance.

Empowering Awareness and Acceptance:

Despite the challenges, many individuals with vitiligo have embraced their unique beauty and become advocates for awareness and acceptance. Through social media, awareness campaigns, and community support groups, people with this condition are sharing their stories, challenging stereotypes, and promoting inclusivity.

In conclusion, vitiligo is more than skin deep. It's a condition that affects individuals physically, emotionally, and socially. By understanding the complexities, supporting research for better treatments, and fostering a culture of acceptance and inclusivity, we can empower those living with vitiligo and celebrate the diversity of human beauty with the timeless words of Michael Jackson's song, 'Heal the world, make it a better place for you, and for me and the entire human race.'

References

  1. Joge RR, Kathane PU, Joshi SH. Vitiligo: A Narrative Review. Cureus. 2022 Sep 18;14(9):e29307. doi: 10.7759/cureus.29307. PMID: 36304341; PMCID: PMC9586189.
  2. Jan NA, Masood S. Vitiligo. Treasure Island (FL): StatPearls Publishing; 2024 Jan
  3. https://vitiligozone.com/people/hedvig-lindahl-interview
  4. https://livingdappled.com/17-famous-people-with-vitiligo/#:~:text=To%20date%2C%20perhaps%20the%20most,to%20share%20their%20stories%20publicly.
  5. https://michaeladeprince.com/about/

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